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3-Methylaminopiperidine dihydrochloride

Orukọ ọja:

3- (Methylamino) piperidine Dihydrochloride;

N-methylpiperidin-3-amine, dihydrochloride;

3- (Methylamino) piperidine dihydrochloride;

N-Methylpiperidin-3-amine dihydrochloride;

3-Methylaminopiperidine dihydrochloride;


Ọja Awọn ẹya ara ẹrọ

1.Cas No: 127294-77-3
2.Molecular agbekalẹ: C6H16Cl2N2
3.Chemical Structure

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4.Melting ojuami: 199-200 ° C
5.Sisun ojuami: 253.7ºC
Awọn ipo 6.Storage: Fipamọ ni itura, ibi gbigbẹ.

Ohun elo: Agbedemeji pataki fun iṣelọpọ ti fluoroquinolone antibacterial oògùn balofloxacin.

Iṣaaju:3-methylaminoperidine (1) jẹ agbedemeji pataki fun iṣelọpọ ti fluoroquinolone antibacterial oògùn balofloxacin.Awọn litireso naa nlo γ-butyrolactone bi ohun elo aise ati pe o gba amination, hydrolysis, esterification, ati bromine.Ethyl acetate condensation, cyclization, ester hydrolysis ati decarboxylation, reductive amination ati hydrogenolysis debenzyl lenu lati gba 3-methylaminopperidine, awọn ilana ti Kemikali ni o gun, ati awọn lapapọ ikore jẹ kekere (nikan 11,5%).Lo 3-aminopyridine (2) lati gba 3-methylaminopyridine (4) nipasẹ iṣelọpọ ati idinku pẹlu litiumu aluminiomu hydride;tabi condense pẹlu 2 ati triethyl orthoformate ati ki o din pẹlu sodium borohydride lati gba 4,4.Idinku ti Pd/C lati mura 3-methylaminoperidine diacetate pẹlu awọn eso lapapọ ti 16% ati 32%, lẹsẹsẹ.

Ẹka:Iwọn nitrogen; piperidine; agbedemeji; reagent gbogbogbo; agbedemeji baloxacin; agbedemeji elegbogi; Piperidine; Awọn akopọ Heterocyclic.

 

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A ni o wa Princechem Pharmaceutical olupese kọja 20 years iriri.Awọn oriṣi ti awọn aati kemikali ni etherification, amoniation, chlorination, esterification, cyclization, hydrogenation and Grignard reaction, bbl..Ni awọn ọdun 10 sẹhin, diẹ sii ju awọn ọja katalogi 400 ni idagbasoke.Ni awọn ọdun aipẹ, diẹ sii ju awọn oriṣi 40 ti awọn agbedemeji elegbogi bọtini ni a ti ni idagbasoke, pẹlu egboogi-akàn, iṣan inu ọkan ati ẹjẹ, eto ounjẹ, awọn arun ọpọlọ ati awọn aaye miiran.O pẹlu awọn agbedemeji bọtini ti API.Fun ọpọlọpọ ọdun, a ti n pese awọn agbedemeji elegbogi didara giga fun ọpọlọpọ awọn ile-iṣẹ oogun olokiki olokiki agbaye.

Idawọlẹ HI-Tech jẹ ọlá fun YPC ni ọdun 2011. Ile-iṣẹ naa faramọ imọ-jinlẹ ati imotuntun imọ-ẹrọ ati pe o ni diẹ sii ju awọn iwe-aṣẹ kiikan 10 ti a fun ni aṣẹ.

YPC ta ku lori lilo awọn eto iṣakoso boṣewa agbaye lati ṣe igbelaruge awọn iṣakoso wa ati ti ṣeto awọn eto ISO9001:2000, ISO14001:2004 ati OHS18001:1999.Ni awọn ọdun diẹ sẹhin, o ti kọja awọn iṣayẹwo lori aaye nipasẹ diẹ sii ju 20 okeere ati awọn ile-iṣẹ oogun ile.

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